Frozen Ark

10 July 2019 Steven MacKenzie

Frozen Ark

Noah had it wrong. Animals coming two-by-two would doom them to inbreeding their way to non-existence. But Noah had the right idea too. Long before there were David Attenborough documentaries, he realised that the beasts of the Earth needed a helping hand from humans to survive (even if it was also our hand that caused their demise). Today, as the United Nations warns that one million animal and plant species are headed towards extinction, conservation is critical.

Professor Mike Bruford of Cardiff University is taking a leaf out of the Bible, but dropping the temperature. He is director of the Frozen Ark Project, which collects and preserves DNA and tissue samples of endangered animals.

The Big Issue: Is this how Noah would do it nowadays?

Professor Mike Bruford: There’s no substitute for real animals, but the idea of doing it “two-by-two” is problematic! In reality, we need to conserve as much genetic diversity for each species as possible, and just two individuals isn’t anything near enough.

If the ark isn’t on a boat, where is it?

The ark is a network of locations where we have freezers that can preserve samples for the very long term. If the freezers break down or there’s a power cut in one place, we have a viable back-up in another place.

Does the frozen ark focus on endangered animals?

Yes, the frozen ark only keeps genetic material from endangered species – and we have all sorts from all over the world, from tiny tree snails from the Pacific, to snow leopards, elephants and antelopes. But there are other arks (for example, there is one for European zoos) that have samples for more common species, because even those species are in decline. Animals that are common and declining today may become endangered tomorrow.

What does a sample actually consist of?

Just a really small amount is needed, usually a few micrograms of DNA (a microgram is one millionth of a gram) is all we need. But we sometimes keep tissue (a few millilitres of blood, for example) and we keep cell cultures and sperm samples too.
How are samples collected?

It varies. In zoos, when animals are undergoing health checks and are having blood or tissue biopsies we can take a small sample. Occasionally, when animals die we can take samples. For very rare species, which are being studied in their natural habitat, we may even accept poo samples – but the poo has to be very fresh!

Does the frozen ark hold any species on the verge of extinction?

Yes, sadly it does (including the tree snails I mentioned), and even sadder, it contains samples for many populations and subspecies of animals that have gone extinct. There are a lot of populations of animals that I have studied myself that have gone extinct over the 30 years I have been doing this kind of science. For example, we have genetic samples of the western black rhinoceros that lived in Cameroon but was declared extinct in 2010.

Why is this an important project in today’s world?

If we don’t do this, species will lack the genetic diversity they need to survive future climate change, habitat fragmentation, and the environmental degradation and destruction that man is inflicting on the planet. Genetic diversity is a prerequisite for evolution to happen, as [Charles] Darwin appreciated. Evolution is the way that individuals and populations adapt to their new circumstances.

So it’s less about resurrecting extinct animals and more about preserving the genetic diversity of those still around?

We do preserve DNA for the far future, because it is impossible to predict what technology might bring in 100 years’ time. But we are very focused on conserving DNA that can help research and conservation now. One way is by using sperm from animals that died decades ago to add “new” genetic material to species undergoing conservation management in the present day.

How can we make sure we’ve learned the lessons of Jurassic Park?

Scientists will always push boundaries – it is what we do! We don’t have the technology to recreate a dinosaur, and even if we could create the organic structures that make a living animal, it would be out of context because the world has changed radically since its genome evolved to make it exist. It would not know how to behave, it would be susceptible to all the diseases on the planet that have evolved since it went extinct and much of the way animals live are due to “nurture” as opposed to “nature” – so it wouldn’t know how to survive. Cloning of animals is already done (as in Dolly the Sheep) but clones by definition have no genetic diversity, and the point of the frozen ark is to conserve genetic diversity!

By Steve MacKenzie, The Big Issue UK

» Appeared in Ed#590